GOmixer - Reference data : GMMs-BSB-1.0

A high-level metabolic map that gives an overview of the major metabolic processes in the gut

Tip: Click a metabolic process on the map to list its metabolic modules.

This metabolic map consists of gut-specific pathway modules connected by their input and output compounds. The modules are clustered and colored according to their hierarchical classification (e.g. amino-acid degradation). Metabolites are represented by circles, while modules are represented by colored lines. The flow of compounds is from top to bottom unless the module is represented by a dashed line.

Id	Name	Hierarchy, Level 1	Hierarchy, Level 2
MF0001	ethanol production (formate pathway)	alcohol metabolism	ethanol metabolism
MF0002	ethanol production (CO2 pathway)	alcohol metabolism	ethanol metabolism
MF0003	acetylglucosamine degradation	amines and polyamines degradation	acetylglucosamine degradation
MF0004	putrescine degradation	amines and polyamines degradation	biogenic amine degradation
MF0005	acetylneuraminate and acetylmannosamine degradation	amines and polyamines degradation	sialic acid degradation
MF0006	urea degradation	amines and polyamines degradation	urea degradation
MF0007	phenylalanine degradation	amino acid degradation	aromatic amino acid degradation
MF0008	tyrosine degradation (hydroxyphenylacetaldehyde pathway)	amino acid degradation	aromatic amino acid degradation
MF0009	tryptophan degradation	amino acid degradation	aromatic amino acid degradation
MF0010	tyrosine degradation (phenol pathway)	amino acid degradation	aromatic amino acid degradation
MF0011	aspartate degradation (oxaloacetate pathway)	amino acid degradation	negatively charged amino acid degradation
MF0012	aspartate degradation (fumarate pathway)	amino acid degradation	negatively charged amino acid degradation
MF0013	glutamate degradation (crotonyl-CoA pathway)	amino acid degradation	negatively charged amino acid degradation
MF0014	glutamate degradation (4-aminobutanoate pathway)	amino acid degradation	negatively charged amino acid degradation
MF0015	glutamate degradation (methylaspartate pathway)	amino acid degradation	negatively charged amino acid degradation
MF0016	glycine degradation	amino acid degradation	nonpolar, aliphatic amino acid degradation
MF0017	alanine degradation (racemase pathway)	amino acid degradation	nonpolar, aliphatic amino acid degradation
MF0018	proline degradation (glutamate pathway)	amino acid degradation	nonpolar, aliphatic amino acid degradation
MF0019	proline degradation (aminopentanoate pathway)	amino acid degradation	nonpolar, aliphatic amino acid degradation
MF0020	valine degradation	amino acid degradation	nonpolar, aliphatic amino acid degradation
MF0021	leucine degradation	amino acid degradation	nonpolar, aliphatic amino acid degradation
MF0022	isoleucine degradation	amino acid degradation	nonpolar, aliphatic amino acid degradation
MF0023	methionine degradation (cysteine pathway)	amino acid degradation	nonpolar, aliphatic amino acid degradation
MF0024	methionine degradation (mercaptan pathway)	amino acid degradation	nonpolar, aliphatic amino acid degradation
MF0025	alanine degradation (glutamate pathway)	amino acid degradation	nonpolar, aliphatic amino acid degradation
MF0026	cysteine biosynthesis/homocysteine degradation	amino acid degradation	polar, uncharged amino acid degradation
MF0027	cysteine degradation	amino acid degradation	polar, uncharged amino acid degradation
MF0028	serine degradation	amino acid degradation	polar, uncharged amino acid degradation
MF0029	threonine degradation (glycine pathway)	amino acid degradation	polar, uncharged amino acid degradation
MF0030	threonine degradation (formate pathway)	amino acid degradation	polar, uncharged amino acid degradation
MF0031	asparagine degradation	amino acid degradation	polar, uncharged amino acid degradation
MF0032	glutamine degradation (ammonia pathway)	amino acid degradation	polar, uncharged amino acid degradation
MF0033	cysteine degradation (mercaptopyruvate pathway)	amino acid degradation	polar, uncharged amino acid degradation
MF0034	glutamine degradation (oxoglutarate pathway)	amino acid degradation	polar, uncharged amino acid degradation
MF0035	arginine degradation (agmatine deiminase pathway)	amino acid degradation	positively charged amino acid degradation
MF0036	arginine degradation (ornithine decarboxylase pathway)	amino acid degradation	positively charged amino acid degradation
MF0037	arginine degradation (AST/succinyltransferase pathway)	amino acid degradation	positively charged amino acid degradation
MF0038	arginine degradation (arginine:pyruvate transaminase/4-aminobutyrate pathway)	amino acid degradation	positively charged amino acid degradation
MF0039	lysine fermentation to acetate and butyrate (3,6-diaminohexanoate pathway)	amino acid degradation	positively charged amino acid degradation
MF0040	lysine degradation (cadaverine pathway)	amino acid degradation	positively charged amino acid degradation
MF0041	histidine degradation	amino acid degradation	positively charged amino acid degradation
MF0042	4-aminobutyrate degradation	amino acid degradation	positively charged amino acid degradation
MF0043	arginine degradation (agmatinase pathway)	amino acid degradation	positively charged amino acid degradation
MF0044	glycocholate degradation	bile acid degradation	glycocholate degradation
MF0045	trehalose degradation	carbohydrate degradation	disaccharide degradation
MF0046	sucrose degradation	carbohydrate degradation	disaccharide degradation
MF0047	lactose and galactose degradation (PTS)	carbohydrate degradation	disaccharide degradation
MF0048	lactose degradation	carbohydrate degradation	disaccharide degradation
MF0049	maltose degradation	carbohydrate degradation	disaccharide degradation
MF0050	melibiose degradation	carbohydrate degradation	disaccharide degradation
MF0051	sucrose degradation (Actinobacteria)	carbohydrate degradation	disaccharide degradation
MF0052	chondroitin sulfate and dermatan sulfate degradation	carbohydrate degradation	glycosaminoglycan degradation
MF0053	allose degradation	carbohydrate degradation	monosaccharide degradation
MF0054	arabinose degradation	carbohydrate degradation	monosaccharide degradation
MF0055	xylose degradation	carbohydrate degradation	monosaccharide degradation
MF0056	galactose degradation (Leloir pathway)	carbohydrate degradation	monosaccharide degradation
MF0057	alpha-D-glucose and alpha-D-glucose 1-phosphate degradation	carbohydrate degradation	monosaccharide degradation
MF0058	fructose degradation	carbohydrate degradation	monosaccharide degradation
MF0059	rhamnose degradation	carbohydrate degradation	monosaccharide degradation
MF0060	ribose degradation	carbohydrate degradation	monosaccharide degradation
MF0061	mannose degradation	carbohydrate degradation	monosaccharide degradation
MF0062	starch degradation	carbohydrate degradation	polysaccharide degradation
MF0063	fructan degradation	carbohydrate degradation	polysaccharide degradation
MF0064	pectin degradation	carbohydrate degradation	polysaccharide degradation
MF0065	pectin degradation - 5-dehydro-4-deoxy-D-glucuronate degradation	carbohydrate degradation	polysaccharide degradation
MF0066	glycogen metabolism	carbohydrate degradation	storage
MF0067	PHB production	carbohydrate degradation	storage
MF0068	glucarate degradation	carbohydrate degradation	sugar acid degradation
MF0069	galactarate degradation	carbohydrate degradation	sugar acid degradation
MF0070	galactonate degradation	carbohydrate degradation	sugar acid degradation
MF0071	D-galacturonate degradation	carbohydrate degradation	sugar acid degradation
MF0072	ribitol degradation	carbohydrate degradation	sugar alcohol degradation
MF0073	sorbitol degradation (dehydrogenase)	carbohydrate degradation	sugar alcohol degradation
MF0074	mannitol degradation	carbohydrate degradation	sugar alcohol degradation
MF0075	sorbitol degradation (phosphotransferase)/sorbose degradation	carbohydrate degradation	sugar alcohol degradation
MF0076	arabitol degradation	carbohydrate degradation	sugar alcohol degradation
MF0077	galactitol degradation	carbohydrate degradation	sugar alcohol degradation
MF0078	xylitol degradation	carbohydrate degradation	sugar alcohol degradation
MF0079	bifidobacterium shunt	central metabolism	energy metabolism
MF0080	Glycolysis (preparatory phase)	central metabolism	energy metabolism
MF0081	Glycolysis (pay-off phase)	central metabolism	energy metabolism
MF0082	pentose phosphate pathway (oxidative branch)	central metabolism	energy metabolism
MF0083	pyruvate dehydrogenase complex	central metabolism	energy metabolism
MF0084	pyruvate:ferredoxin oxidoreductase	central metabolism	energy metabolism
MF0085	pyruvate:formate lyase	central metabolism	energy metabolism
MF0086	TCA cycle	central metabolism	energy metabolism
MF0087	TCA cycle (Mycobacterium pathway)	central metabolism	energy metabolism
MF0088	TCA cycle (Helicobacter pathway)	central metabolism	energy metabolism
MF0089	Entner-Doudoroff pathway I	central metabolism	energy metabolism
MF0090	pentose phosphate pathway (non-oxidative branch)	central metabolism	energy metabolism
MF0091	beta-D-glucuronide and D-glucuronate degradation	glycoprotein degradation	glucuronide degradation
MF0092	kdo2-lipid A synthesis	endotoxin biosynthesis	lipopolysaccharide biosynthesis
MF0093	homoacetogenesis	gas metabolism	acetogenesis
MF0094	hydrogen metabolism	gas metabolism	hydrogen metabolism
MF0095	NADH:ferredoxin oxidoreductase	gas metabolism	hydrogen metabolism
MF0096	methane oxidation	gas metabolism	methane consumption
MF0097	Methanogenesis - methyl-coM	gas metabolism	methanogenesis
MF0098	methanogenesis from carbon dioxide	gas metabolism	methanogenesis
MF0099	methanol conversion	gas metabolism	methanogenesis
MF0100	Sulfate reduction (dissimilatory)	gas metabolism	sulfate metabolism
MF0101	Sulfate reduction (assimilatory)	gas metabolism	sulfate metabolism
MF0102	mucin degradation	glycoprotein degradation	mucus degradation
MF0103	nitrate reduction (assimilatory)	inorganic nutrient metabolism	nitrogen
MF0104	nitrate reduction (dissimilatory)	inorganic nutrient metabolism	nitrogen
MF0105	nitrate reduction (denitrification)	inorganic nutrient metabolism	nitrogen
MF0106	anaerobic fatty acid beta-oxidation	lipid degradation	beta-oxidation
MF0107	glycerol degradation (propanediol pathway)	lipid degradation	glycerol degradation
MF0108	glycerol degradation (dihydroxyacetone pathway)	lipid degradation	glycerol degradation
MF0109	glycerol degradation (glycerol kinase pathway)	lipid degradation	glycerol degradation
MF0110	glyoxylate bypass	lipid degradation	glyoxylate bypass
MF0111	triacylglycerol degradation	lipid degradation	triacylglycerol degradation
MF0112	acetate to acetyl-CoA	organic acid metabolism	acetate metabolism
MF0113	acetyl-CoA to acetate	organic acid metabolism	acetate metabolism
MF0114	acetyl-CoA to crotonyl-CoA	organic acid metabolism	butyrate metabolism
MF0115	Crotonyl-coA from succinate	organic acid metabolism	butyrate metabolism
MF0116	butyrate production via transferase	organic acid metabolism	butyrate metabolism
MF0117	butyrate production via kinase	organic acid metabolism	butyrate metabolism
MF0118	formate conversion	organic acid metabolism	formate metabolism
MF0119	lactate production	organic acid metabolism	lactate metabolism
MF0120	lactate consumption	organic acid metabolism	lactate metabolism
MF0121	propionate production (acrylate pathway)	organic acid metabolism	propionate metabolism
MF0122	propionate production (succinate pathway)	organic acid metabolism	propionate metabolism
MF0123	propionate production (propanediol pathway)	organic acid metabolism	propionate metabolism
MF0124	Fucose degradation	organic acid metabolism	propionate metabolism
MF0125	propionate production via kinase	organic acid metabolism	propionate metabolism
MF0126	propionate production via transferase	organic acid metabolism	propionate metabolism
MF0127	Succinate production	organic acid metabolism	succinate metabolism
MF0128	Propionate conversion to succinate	organic acid metabolism	succinate metabolism
MF0129	catalase	protection against oxidative stress	catalase
MF0130	peroxidase	protection against oxidative stress	peroxidase
MF0131	superoxide dismutase	protection against oxidative stress	superoxide dismutase
MF0132	superoxide reductase	protection against oxidative stress	superoxide reductase
MF0133	menaquinone production	secondary metabolites	vitamins