This metabolic map consists of gut-specific pathway modules connected by their input and output compounds. The modules are clustered and colored according to their hierarchical classification (e.g. amino-acid degradation). Metabolites are represented by circles, while modules are represented by colored lines. The flow of compounds is from top to bottom unless the module is represented by a dashed line.


image/svg+xmlimage/svg+xmlimage/svg+xmlalpha,alpha-TrehaloseD-GalactoseD-Glucose 6-phosphateLactose 6-phosphateAcceptor beta-D-glucuronoside2-Dehydro-3-deoxy-6-phospho-D-gluconateL-2-Amino-4-mercaptobutyric acidL-2-Amino-4methylthiobutyric acidSuccinyl coenzyme A(S)-alpha-Amino-beta-phenylpropionic acid2-Aminosuccinic acid2-Aminosuccinamic acid2-Oxobutanedioic acidL-Selenocysteine2-Ketobutyric acidMethanethiolButanoateAminoacetic acid(6R)-5,10-MethylenetetrahydrofolatePropanoate2-(Methylthio)ethanesulfonateBenzeneacetic acid2-Hydroxypropanal1-HydroxypropaneFumarate2,6-Diaminohexanoic acid1,5-Diaminopentane3-Acetoacetyl-CoAD-Mannitol 1-phosphateD-Mannose 6-phosphateStarch6-O-(alpha-D-Galactopyranosyl)-D-glucopyranosebeta-D-Glucosealpha-D-GalactoseL-ArabinopyranoseL-ArabinoketoseD-Fructose 1-phosphatebeta-D-Fructose 1,6-bisphosphateD-RiboseD-Ribose 5-phosphatebeta-D-Fructanbeta-D-arabino-HexuloseD-GlucitolD-arabino-HexuloseH2O2H2OO2-(6S)-TetrahydrofolateTriacylglycerol1,3-PropanediolD-ArabinitolXylitolD-XyloseD-Xylulose 5-phosphateAdonitolN-Acetyl-D-glucosamine 6-phosphate5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acidD-AlloseCentralmetabolismAlcoholmetabolismGlycoproteindegradationLipiddegradationProtectionagainstoxidative stressGasmetabolismAmino aciddegradationInorganicnutrientmetabolismCarbohydratedegradationBile aciddegradationAmines andpolyaminesdegradationOrganic aciddegradationChorismateMenaquinol2-Amino-3-methylbutyric acid2-Hydroxypropanoic acid2-Pyrrolidinecarboxylic acidDihydrolipoate5-AminopentanoateLipoateSulfate2-Amino-3-hydroxybutyric acidL-2-Amino-3-hydroxypropionic acid(S)-alpha-Amino-beta-(3-indolyl)-propionic acidNitrateL-2-Aminoglutaramic acid(S)-alpha-Amino-1H-imidazole-4-propionic acidGlycogenO2H+Reduced ferredoxinH2Oxidized ferredoxinMethaneH2SHydrogen cyanideL-2-Amino-3-mercaptopropionic acid3alpha,7alpha,12alpha-Trihydroxy-5beta-cholan-24-oylglycineCarbon dioxide2,3-BenzopyrroleFatty acidPoly-beta-hydroxybutyrateN-Acetyl-D-glucosamine(S)-2-Amino-5-guanidinovaleric acid1,4-ButanediamineCarbamide4-AminobutanoateThiocyanate2-Ketoglutaric acid2-Butenoyl-CoAGlutamate2-Amino-3-methylvaleric acidAmmoniaButanedionic acidAcetatePropanoyl-CoAPEPH22-Amino-3-methylbutyric acid(S)-3-Amino-2-methylpropanoate3-Oxobutanoic acid(2S)-alpha-2-Amino-4-methylvaleric acidBenzenolL-2-Aminopropionic acid(S)-2-Amino-3-(p-hydroxyphenyl)propionic acidEndotoxin biosynthesisSecondarymetabolitesDehydrated ethanolFormateAcetyl coenzyme AD-Galacturonate(S)-LactaldehydeD-Galactitol 1-phosphate6-Deoxy-L-galactose6-Deoxy-L-mannosePectinD-GlucarateD-GalactarateD-Galactonate2-Phospho-D-glycerate1,2,3-PropanetriolAcetyl phosphate6-Phospho-D-gluconate2-Oxopropanoate(2R)-2-Hydroxy-3-(phosphonooxy)-propanalD-Fructose 6-phosphateD-Ribulose 5-phosphatealpha-D-Glucopyranosyl-(1->4)-D-glucopyranoseD-gluco-Hexonic acid1-alpha-D-Glucopyranosyl-2-beta-D-fructofuranosidebeta-D-Fructose 6-phosphatealpha-D-Glucosealpha-D-Glucose 1-phosphatebeta-D-Glucose 6-phosphateD-Glucose1-beta-D-Galactopyranosyl-4-alpha-D-glucopyranoseMethanol


A high-level metabolic map that gives an overview of the major metabolic processes in the gut


image/svg+xml CO2 metabolism CO2 Hydrogen metabolism H2 Methane metabolism CH4 #Energy storage Energy storage Butyrate production Butyrate Acetate production Acetate Propionate production Propionate Monosaccharide degradation Monosaccharides Disaccharide degradation Disaccharides Polysaccharide degradation Polysaccharides Sugar acid degradation Sugar acid Mucus degradation MucusDegradation Lipolytic fermentation LipolyticFermentation Proteolytic fermentation ProteolyticFermentation Oxidative stress ROS Nitrate metabolism RNS Acetogenesis Acetogenesis Ethanol production Ethanol central metabolism CentralMetabolism Sugar alcohol degradation Sugar alcohol Ammonia production NH3 Sulfate metabolism Sulfatereduction cross-feeding intermediate metabolism cross-feeding intermediate metabolism Cross-feeding


For a detailed description of the modules please download the module set file (right-click, then save link as).